Contents
 
 Introduction
 
 Overview of Diabetes Type I
 
  What is diabetes type I
           Health implications of diabetes type I
 
 Physical Activity
 
  What is physical activity?
  Why do we need physical activity in our lives?
 
 Physical Activity and Diabetes (Epidemiology)
 
 Conclusion
 
 Bibliography
 
 
 
 Introduction
 
  For our seminar topic "physical activity and disease" we chose diabetes as the focus of our
  research.
 
  Since diabetes is such a complex disease with many different forms, we decided to focus on
  diabetes type I. This is known as insulin-dependent diabetes mellitus (IDDM). This type of
  diabetes includes people who are dependant on injections of insulin on a daily basis in
  order to satisfy the bodies insulin needs, they cannot survive without these injections.
 
 
 
 OVERVIEW OF DIABETES TYPE I
 
  What is diabetes type I?
 
  In order to understand the disease we firstly need to know about insulin. Insulin is a
  hormone. The role of insulin is to convert the food we eat into various useful substances,
  discarding everything that is wasteful.
 
  It is the job of insulin to see that the useful substances are put to best use for our
  well-being. The useful substances are used for building cells, are made ready for immediate
  expenditure as energy and also stored for later energy expenditure.
 
  The cause of diabetes is an absolute or lack of the hormone insulin. As a result of this
  lack of insulin the processes that involve converting the foods we eat into various useful
  substances does not occur.
 
  Insulin comes from the beta cells which are located in the pancreas. In the case of
  diabetes type I almost all of the beta cells have been destroyed. Therefore daily
  injections of insulin become essential to life.
 
 Health implications of diabetes type I
 
 
  One of the products that is of vital importance in our bodies is glucose, a simple
  carbohydrate sugar which is needed by virtually every part of our body as fuel to function.
 
  Insulin controls the amount of glucose distributed to vital organs and also the muscles. In
  diabetics due to the lack of insulin and therefore the control of glucose given to
  different body parts they face death if they don't inject themselves with insulin daily. 
 
  Since strict monitoring of diabetes is needed for the control of the disease, little room
  is left for carelessness. As a result diabetic patients are susceptible to many other
  diseases and serious conditions if a proper course of treatment is not followed. 
 
  Other diseases a diabetic is open to: Cardiovascular disease, stroke, Peripheral artery
  disease, gangrene, kidney disease, blindness, hypertension, nerve damage, impotence etc.
  Basically there is an increased incident of infection in diabetic sufferers. Therefore
  special care needs to be taken to decrease the chances of getting these other serious
  diseases.
 
 
 
 PHYSICAL ACTIVITY
 
 What is physical activity?
 
  (Bouchard 1988) States that physical activity is any bodily movement produced by skeletal
  muscles resulting in energy expenditure. Therefore this includes sports and leisure
  activities of all forms.	
 
 Why do we need physical activity in our lives?
  Physical activity and exercise helps tune the "human machine", our bodies.
 
  Imagine a car constantly driven only to stop for  fuel. It would be a client for all sorts
  of damage, rusting, oil leaking, dehydration and the chances are most likely it would die
  in the middle of the road not long after. This is what the body would be like if we didn't 
  exercise at all. We would be and as a result of todays lifestyle many of us are,  the
  perfect target to all kinds of diseases and infections.
 
  For those of us who are carrier of some disease or illness we are still encouraged to
  exercise by our physicians if we have the strength to. This is to help make our organs,
  muscles, bones and arteries more efficient and better equipped to fight against the disease
  or illness. This is our way of counter attacking. And if we are still healthy then we
  reduce the chances of  getting an illness or a disease. 
 
 PHYSICAL ACTIVITY AND DIABETES (EPIDEMIOLOGY)
 
  Recently insulin injections have become available to dependant patients. However in the
  pre-insulin era physical exercise was one of  the few therapies available to physicians in
  combating diabetes.
 
  For an IDDM carrier to benefit from exercise they need to be well aware of their body and
  the consequences of exercising.
 
  If an IDDM carrier has no real control over their situation and just exercise without
  considering their diet, time of insulin intake, type of exercise, duration of the exercise
  and the intensity, then the results can be very hazardous to the patient.
 
  In the first journal article that I used for this part of the research (Sutton 1981) had
  conducted an investigation on "drugs used in metabolic disorders". The article is designed
  to provide some background information on previous beliefs and research conducted early
  this century. As well as his own investigations conducted during the beginning of the
  1980's. He has compared the results and came to the same conclusion as the investigations
  done early in this century.  
 
 
  Sutton's findings show that decrease in blood glucose following an insulin injection was
  magnified when the insulin was followed by physical activity/exercise (see figure 1). This
  shows that if a person gets involved in physical activity or exercise after insulin the
  volume of glucose drops dramatically. This leads to symptoms of hypoglycemia. The reason
  this occurs is that glucose uptake by muscles increase during exercise, in spite of no
  change or even a diminishing plasma insulin concentration.  As a result of this type of
  information we know now that if a patient is not controlled through a good diet and program
  then they could put themselves in danger. A person who might be poorly maintained and
  ketotic will become even more ketotic and hypoglycimic.
 
  Good nutrition is of great importance to any individual especially one that exercises. In
  the case of diabetes even more consideration must go into the selection of food before and
  after exercise. Doctors suggest large intakes of carbohydrates before exercise for diabetes
  carriers to meet the glucose needs of the muscles.
  
 
 
  The second article that I used was that of Konen, et al. He and his colleagues conducted
  testing and research on "changes in diabetic urinary and transferrin excretion after
  moderate exercise". This article was a report of the way the research was conducted and
  it's findings. 
 
  The researched found that urinary proteins, particularly albumin, increase in urinary
  excretion after moderate exercise. Albumin which is associated with micro- and
  macrovascular diseases in diabetic patience was found to increase significantly in IDDM
  patients, while remaining normal in non-diabetics. (See table 1 and 2 for results)
 
 
 
  These results cannot be conclusive to say that this shows that exercise causes other micro-
  and macrovascular diseases in diabetics. Since albumin is not associated with any disease
  in non-diabetics then the same may be the case for diabetics as well. However further
  research is required to find out why such a significant increase occurs in diabetic
  patients and what it really means.
 
  It obvious that there are many very complicated issues associated with diabetes which
  cannot be explained at this stage. Therefore much more research is required and it's only a
  matter of time for these complications to resolved.
 
  Although there are no firm evidence to suggest that exercise will improve or worsen
  diabetes still it is recommended by physicians.
 
  Aristotle and the Indian physician, Sushruta, suggested the use of exercise in the
  treatment of diabetic patients as early as 600 B.C. And during late last century and early
  this century many physician claimed that the need for insulin decreased in exercising
  patients.
 
  The benefits of exercise in non-diabetic individuals is well known. For example reduce the
  risk of heart disease. This makes exercise very important to diabetic carriers since they
  are at a greater risk of getting heart disease than non-diabetics.
 
  Unquestionably, it's important for diabetics to optimise cardiovascular and pulmonary
  parameters as it is for non-diabetic individual. Improved fitness can improve one's sense
  of well-being and ability to cope with physical and psychological stresses that can be
  aggravated in diabetes.
 
  In well controlled exercise programs the benefits are many, as shown on table 3.   
 
 
 
 CONCLUSION
 
 
  In conclusion we can see that although there are many factors that need to considered when
  a diabetic person exercises, still there are many benefits when an IDDM carrier controls
  and maintains a good exercise program. The risks of other disease such as heart disease and
  obesity are reduced.
 
 
 
 Bibliography
 
 
 
 
  1. Sutton, J.R, (1981), Drugs used in metabolic disorders, Medicine and Science in Sports
  and Exercise, Vol 13, pages 266-271.
 
  2. Konen, J.C, (1993), Changes in diabetic urinary transferrin excretion after moderate
  exercise, Medicine and Science in Sports and Exercise, pages 1110-1114.
 
  3. Bouchard, C, (1990), Exercise, Fitness and Health, Human Kinetics Publishers.
 
  4. Burke, E.J,  (1980), Exercise, Science and Fitness, Mouvement Publishers.
 
  5. Sanborn, M.A, (1980), Issues in Physical Education, Lea and Febiger.
 
  6. Marble, A, (1985), Joslin's Diabetes Mellitus, Twelfth Edition, Lea and Febiger.
 
  7. Kilo, C, (1987), Diabetes - The facts that let you regain control of your life, John
  Wiley and Sons, Inc.
 
  8. Seefeldt, V, (1986), Physical Activity and Well-being, American Alliance for Health,
  Physical Education, Recreation and Dance.
 
 
 